MY MENTOR & I PERSPECTIVE
Bone homeostasis and energy metabolism after cold stress challenge in mice
Weight gain occurs when energy intake from food exceeds energy expenditure, while restricting caloric intake to a value below that is needed for daily energy expenditure results in weight loss. Energy expenditure increases during exposure to cold and the regulation of body temperature is one of the most critical function of the nervous system. In this perspective we will describe some of the newly discovered physiological circuits activated by thermogenic challenge and their involvement in bone and energy metabolism.
Elena Conte, PhD, is a post-doctoral fellow in the Department of Pharmacy-Drug Sciences at the University Aldo Moro in Bari. Her research focuses on the characterization of skeletal muscle function and bone metabolism in different pathophysiological conditions through in vivo and ex vivo studies on animal models. Her studies are leading to the identification of molecular targets for new drugs and to the development of individualized treatments in skeletal muscle-related pathologies.
Claudia Camerino, PhD, is an assistant professor of medicine in the Department of Biomedical Sciences and Human Oncology, School of Medicine, University of Bari and in the Department of Physiology and Pharmacology “V. Erspamer”, SAPIENZA University in Rome. Her main research topics are the physiological functions of hormones/neurotransmitters in the regulation of bone and energy metabolism. She developed a special interest for the role of Oxytocin in the development of obesity and muscular diseases.